Vertebrale Hyperostosis

Isotretinoin-induced skeletal hyperostosis

We describe a case of skeletal hyperostosis in a 29 year old man presenting with non-inflammatory back pain with a past history of isotretinoin therapy for acne. The development of skeletal hyperostosis, predominantly of the spine, has been reported in association with isotretinoin use and has a radiographic picture similar to diffuse idiopathic skeletal hyperostosis. The prevalence and severit...

The Etiology of Hyperostosis

Hyperostosis cranii or metabolic craniopathy was first recognised as an essential part of Morgagni’s syndrome of virilism, obesity and hyperostosis frontalis. It is a syndrome of uncertain origin which was believed to occur almost exclusively in middle aged and elderly women. More recently it has been shown to occur in younger women and rarely to occur in men. The syndrome is characterised by t...

[Infantile cortical hyperostosis].

The genetic aspects of infantile cortical hyperostosis are discussed. A pedigree is presented, based on the history and clinical and radiological investigations of all living members of the family, with data from 11 cases with the condition in two generations, and one possible case from a third generation. The data suggest that an autosomal dominant gene with varying expressivity could be respo...

Treatment-Refractory Sternocostoclavicular Hyperostosis.

Sternocostoclavicular hyperostosis (SCCH) is an infrequent chronic inflammatory disorder of the axial skeleton of unknown origin. SCCH goes often unrecognized due to a low level of awareness for the disorder. It typically presents with relapsing and remitting pain in the shoulder, neck, and anterior chest wall area with occasional swelling and tenderness of the sternoclavicular area. The diagno...

هیپراستوز ورتبرال آنکیلوزانت HYPERROSTOSE VERTEBRALE ANKYLOSANTE

Vascular involvement in cranial hyperostosis.

Various skeletal dysplas ias known to produce c ranial hyperostosis include osteopetrosis, c rani ometaphyseal dysplas ia, hereditary hyperphosphatasia, Van Buchem disease, and Engelmann disease [1]. Neurologic compl ications such as optic atrophy, facial paralysis, or deafn ess may result from progressive encroachment on the cranial foramina due to bony overgrowth at the base of the skull . Na...